You can configure a plugin to run in a dedicate process, or even in its own process.

![]{cs}(Reaper_Plugin_RunAs_001.png) 

See [reaper.blog](https://reaper.blog/2012/02/run-plugin-as-dedicated-process/)

* Native runs the plugin in the same process as Reaper. If it crashes, it brings down Reaper.
* Separate puts all 'separate' plugins in the same process, separate from Reaper. If one crashes, it brings down all separate plugins, but not Reaper.
* Dedicated runs each plugin instance in its own process.

I use dedicated for plugins like Largo 2 (which crashes if you change the channel count on a track), and plenty of IK stuff.