Serum

From the yabridge readme

Serum requires you to disable d2d1.dll in winecfg and to install gdiplus through winetricks. You may also want to disable the tooltips by going to the global settings tab, unchecking 'Show help tooltips', and clicking on the save icon next to 'Preferences'.

winetricks gdiplus

Dxvk

Some plugins UI's don't update properly unless you install dxvk. On some of my machines the plugins still don't work properly.

winetricks dxvk